Tommy Lam

Liu W, Fan H, Raghwani J, Lam TT, Li J, Pybus OG, Yao HW, Wo Y, Liu K, An XP, Pei GQ, Li H, Wang HY, Zhao JJ, Jiang T, Ma MJ, Xia X, Dong YD, Zhao TY, Jiang JF, Yang YH, Guan Y, Tong Y, Cao WC (2014) Occurrence and reassortment of avian influenza A (H7N9) viruses derived from coinfected birds in China. Journal of Virology 88:13344-51

Lam TT, Wang J, Shen Y, Zhou B, Duan L, Cheung CL, Ma C, Lycett SJ, Leung CY, Chen X, Li L, Hong W, Chai Y, Zhou L, Liang H, Ou Z, Liu Y, Farooqui A, Kelvin DJ, Poon LL, Smith DK, Pybus OG, Leung GM, Shu Y, Webster RG, Webby RJ, Peiris JS, Rambaut A, Zhu H, Guan Y (2013) The genesis and source of the H7N9 influenza viruses causing human infections in China. Nature 502:241-4

Bhatt S, Lam TT, Lycett SJ, Leigh Brown AJ, Bowden TA, Holmes EC, Wood JLN, Brown IH, Kellam P, COSI consortium, Pybus OG (2013) The evolutionary dynamics of influenza A virus adaptation to mammalian hosts. Philosophical Transactions of the Royal Society Series B 368:20120382

Lam TT, Liu W, Bowden TA, Cui N, Zhuang L, Liu K, Zhang YY, Cao WC, Pybus OG (2013) Evolutionary and molecular analysis of the emergent severe fever with thrombocytopenia syndrome virus. Epidemics 5:1-10

Cotton M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P, Pybus OG, Rambaut A, Guan Y, Pillay D, Kellam P, Nastouli E (2013) Full genome deep sequencing and phylogenetic analysis of a novel human betacoronavirus. Emerging Infectious Diseases 19:736-742

Lam TT, Chong YL, Shi M, Hon CC, Li J, Martin DP, Tang JWT, Mok CK, Shih SR, Yip CW, Jiang J, Hui RKH, Pybus OG, Holmes EC, Leung FCC (2013) Systematic phylogenetic analysis of influenza A virus reveals many novel mosaic genome segments. Infection, Genetics & Evolution 18:367-78


Feng Y, He X, Hsi JH, Li F, Li X, Wang Q, Ruan Y, Xing H, Lam TT, Pybus OG, Takebe Y, Shao Y (2013) The rapidly-expanding CRF01_AE epidemic in China is driven by multiple lineages of HIV-1 viruses introduced in the 1990s. AIDS 27:1793-802

Lam TT, Hon CC, Lemey P, Pybus OG, Shi M, Tun HM, Li J, Jiang J, Holmes EC, Leung FC (2012) Phylodynamics of H5N1 avian influenza virus in Indonesia. Molecular Ecology 21:3062-77

Lam TT, Zhu H, Smith DK, Guan Y, Holmes EC, Pybus OG (2012) The recombinant origin of emerging human norovirus GII.4/2008: intra-genotypic exchange of the capsid P2 domain. Journal of General Virology 93:817-22

Tee KK, Lam TT, Chan YF, Bible JM, Kamarulzaman A, Tong CY, Takebe Y, Pybus OG (2010) Evolutionary genetics of human enterovirus 71: origin, population dynamics, natural selection, and seasonal periodicity of the VP1 gene. Journal of Virology 84:3339-50

Lam TT, Hon CC, Pybus OG, Kosakovsky Pond SL, Wong RT, Yip CW, Zeng F, Leung FC (2008) Evolutionary and transmission dynamics of reassortant H5N1 influenza virus in Indonesia. PLOS Pathogens 4:e1000130

Research Associate

Division of Public Health Laboratory Sciences

School of Public Health

University of Hong Kong

Selected Publications

I study the molecular evolution and epidemiology of viruses that cause human and animal diseases. My present research focuses on human, avian and swine influenza. I also work on several other viruses, including HIV-1, dengue virus, adenoviruses, enterovirus-71, noroviruses, infectious bursal disease virus, infectious salmon anaemia virus, SARS coronavirus, rabies virus, PRRSV, porcine circovirus and the West Nile virus. I am interested in the evolutionary biology and comparative genomics of other organisms, such as the giant panda and the tubercles bacillus.

Research Interests