Marina Escalera-Zamudio

EMBO Postdoctoral Fellow

Department of Zoology

University of Oxford

Peter Medawar Building

South Parks Road

Oxford, OX1 3SY, UK

I am interested in how ecological interactions between viruses and their hosts have influenced evolutionary processes. In my previous work I studied the eco-immunological and evolutionary dynamics of vampire bats and the viruses that they host. My current research involves the development of comparative phylogenetic and structural approaches to detect parallel molecular evolution in RNA viruses associated with human and animal disease, with a particular focus on the evolution and emergence of virulence. Although motivated by basic research questions, these results may help to reveal targets for the development of ‘universal’ vaccines and antiviral drugs, and could be validated further through functional assays.

Gutierrez B, Escalera-Zamudio M, Pybus OG (2019) Parallel molecular evolution and adaptation in viruses. Current Opinion in Virology 34:90–96

Zepeda Mendoza ML, Xiong Z, Escalera-Zamudio M, Runge AK, Thézé J, Streicker D, Frank HK, Loza-Rubio E, Liu S, Ryder OA, Castruita JAS, Katzourakis A, Taboada B, Löber U, Pybus OG, Li Y, Rojas-Anaya E, Bohmann K, Baez AC, Arias CF, Liu S, Greenwood AD, Bertelsen MF, White NE, Bunce M, Zhang G, Sicheritz-Pontén T, Gilbert MTP (2018) Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat. Nature Ecology & Evolution 2:659

Escalera-Zamudio M, Taboada B, Rojas-Anaya E et al. (2018) Viral communities among sympatric vampire bats and cattle. EcoHealth 15:132

Escalera-Zamudio M, Rojas-Anaya E, Kolokotronis S, Taboada B, Loza-Rubio E, Méndez-Ojeda ML, Arias CF, Osterrieder N, Greenwood AD (2016) Bats, primates, and the evolutionary origins and diversification of mammalian gammaherpesviruses. mBio 7:e01425-16

Escalera‐Zamudio M, Greenwood AD (2016) On the classification and evolution of endogenous retrovirus: human endogenous retroviruses may not be ‘human’ after all. APMIS 124:44-51

Escalera-Zamudio M, Zepeda-Mendoza ML, Loza-Rubio E, Rojas-Anaya E, Méndez-Ojeda ML, Arias CF, Greenwood AD (2015) The evolution of bat nucleic acid-sensing Toll-like receptors. Molecular Ecology 24:5899-909

Escalera-Zamudio M, Mendoza ML, Heeger F, Loza-Rubio E, Rojas-Anaya E, Méndez-Ojeda ML, Taboada B, Mazzoni CJ, Arias CF, Greenwood AD (2015) A novel endogenous betaretrovirus in the common vampire bat (Desmodus rotundus) suggests multiple independent infection and cross-species transmission events. Journal of Virology 89:5180-4

Escalera-Zamudio M, Nelson MI, Cobián Güemes AG, López-Martínez I, Cruz-Ortiz N, Iguala-Vidales M, García ER, Barrera-Badillo G, Díaz-Quiñonez JA, López S, Arias CF, Isa P; Members of Colegio de Pediatría del Estado de Veracruz (2014) Molecular epidemiology of influenza A/H3N2 viruses circulating in Mexico from 2003 to 2012. PLoS ONE 9:e102453

Escalera-Zamudio M, Cobián-Güemes G, de los Dolores Soto-del Río M, Isa P, Sánchez-Betancourt I, Parissi-Crivelli A, Martínez-Cázares MT, Romero P, Velázquez-Salinas L, Huerta-Lozano B, Nelson M, Montero H, Vinuesa P, López S, Arias CF (2012) Characterization of an influenza A virus in Mexican swine that is related to the A/H1N1/2009 pandemic clade. Virology 433:176-82

Research Interests

Selected Publications