Marina Escalera

EMBO Postdoctoral Fellow

Department of Zoology

University of Oxford

Peter Medawar Building

South Parks Road

Oxford, OX1 3SY, UK

I am interested in how ecological interactions among different hosts have influenced both virus and host evolution. In my previous work, I studied the eco-immunological and evolutionary dynamics of vampire bats and the viruses that they host. My current research project involves the development of comparative approaches to describe molecular evolutionary processes in viral groups that are associated with human and animal disease, and the application of such approaches to large genomic datasets, with a particular focus on evolutionary patterns associated with the emergence of virulence. This project may help to reveal targets for the development of ‘universal’ vaccines and antiviral drugs, which could be further validated through functional assays.

Escalera-Zamudio M, Rojas-Anaya E, Kolokotronis S, Taboada B, Loza-Rubio E, Méndez-Ojeda ML, Arias CF, Osterrieder N, Greenwood AD (2016) Bats, primates, and the evolutionary origins and diversification of mammalian gammaherpesviruses. mBio 7:e01425-16

Escalera-Zamudio M, Zepeda-Mendoza ML, Loza-Rubio E, Rojas-Anaya E, Méndez-Ojeda ML, Arias CF, Greenwood AD (2015) The evolution of bat nucleic acid-sensing Toll-like receptors. Molecular Ecology 24:5899-909

Escalera-Zamudio M, Mendoza ML, Heeger F, Loza-Rubio E, Rojas-Anaya E, Méndez-Ojeda ML, Taboada B, Mazzoni CJ, Arias CF, Greenwood AD (2015) A novel endogenous betaretrovirus in the common vampire bat (Desmodus rotundus) suggests multiple independent infection and cross-species transmission events. Journal of Virology 89:5180-4

Escalera-Zamudio M, Nelson MI, Cobián Güemes AG, López-Martínez I, Cruz-Ortiz N, Iguala-Vidales M, García ER, Barrera-Badillo G, Díaz-Quiñonez JA, López S, Arias CF, Isa P; Members of Colegio de Pediatría del Estado de Veracruz (2014) Molecular epidemiology of influenza A/H3N2 viruses circulating in Mexico from 2003 to 2012. PLoS ONE 9:e102453

Escalera-Zamudio M, Cobián-Güemes G, de los Dolores Soto-del Río M, Isa P, Sánchez-Betancourt I, Parissi-Crivelli A, Martínez-Cázares MT, Romero P, Velázquez-Salinas L, Huerta-Lozano B, Nelson M, Montero H, Vinuesa P, López S, Arias CF (2012) Characterization of an influenza A virus in Mexican swine that is related to the A/H1N1/2009 pandemic clade. Virology 433:176-82

Research Interests

Key Publications