Kenneth Hoehn

DPhil Student

Room D53

Department of Zoology

University of Oxford

South Parks Road

Oxford, OX1 3PS, UK

My research focuses on the development and application of evolutionary and phylodynamic methods to understand how the genetic diversity of the immune system changes in response to viral infection and other stimuli. I am particularly interested in how HIV infection and treatment affects B-cell populations.

Research Interests

Hoehn KB, Lunter G, Pybus OG (2017) A phylogenetic codon substitution model for antibody lineages. Genetics In press

Hoehn KB, Fowler A, Lunter G, Pybus OG (2016) The diversity and molecular evolution of B cell receptors during infection. Molecular Biology & Evolution 33:1147–57

Hoehn KB, Gall A, Bashford-Rogers R, Fidler SJ, Kaye S, Weber JN, McClure MO, SPARTAC Trial Investigators, Kellam P, Pybus OG (2015) Dynamics of immunoglobulin sequence diversity in HIV-1 infected individuals. Philosophical Transactions of the Royal Society B 370:20140241

Hoehn KB, Harnik PG, Roth VL (2016) A framework for detecting natural selection on traits above the species level. Methods in Ecology and Evolution 7:331–9

Hoehn KB, Noor MA (2014) How big is your Y? A genome-sequence based estimate of the size of the male-specific region in Megaselia scalaris. G3 5:45-8

Hoehn KB, McGaugh SE, Noor MA (2012) Effects of premature termination codon polymorphisms in the Drosophila pseudoobscura subclade. Journal of Molecular Evolution 75:141-50

Stevison LS, Hoehn KB, Noor MA (2011) Effects of inversions on within- and between-species recombination and divergence. Genome Biology & Evolution 3:830-41

Publications