Darlan Cândido

DPhil Student

Department of Zoology

University of Oxford

Peter Medawar Building

South Parks Road

Oxford, OX1 3SY, UK

I am interested in phylogenetics and phylogeography as tools to recreate and understand the determinants of viral outbreaks and how this information can be translated into public policy recommendations. More specifically, my research focuses on recent arboviral outbreaks in Latin America (Zika, chikungunya, dengue and yellow fever viruses), combining genetic, spatial and ecological information. My research is supported by the Oxford University Clarendon Fund and the Department of Zoology. Originally a pharmacist and an immunologist, my past research focused on the epidemiology and basic biology of chronic Chagas’s disease cardiomyopathy.

Research Interests

Publications

Ferreira LRP, Ferreira FM, Laugier L, Cabantous S, Navarro IC, da Silva Cândido D, Rigaud VC, Real JM, Pereira GV, Pereira IR, Ruivo L, Pandey RP, Savoia M, Kalil J, Lannes-Vieira J, Nakaya H, Chevillard C, Cunha-Neto E (2017) Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection. Scientific Reports 7:17990

Ferreira LR, Ferreira FM, Nakaya HI, Deng X, Cândido DD, de Oliveira LC, Billaud JN, Lanteri MC, Rigaud VO, Seielstad M, Kalil J, Fernandes F, Ribeiro AL, Sabino EC, Cunha-Neto E (2017)  Blood gene signatures of Chagas cardiomyopathy with or without ventricular dysfunction. Journal of Infectious Diseases 215:387-395

Frade AF, Laugier L, Ferreira LR, Baron MA, Benvenuti LA, Teixeira PC, Navarro IC, Cabantous S, Ferreira FM, da Silva Cândido D, Gaiotto FA, Bacal F,Pomerantzeff P, Santos RH, Kalil J, Cunha-Neto E, Chevillard C (2016) Myocardial infarction-associated transcript, a long noncoding RNA, is overexpressed during dilated cardiomyopathy due to chronic Chagas disease. Journal of Infectious Diseases 214:161-5

Pereira Ldos S, Freitas EC, Fidalgo AS, Andrade MC, Cândido Dda S, da Silva Filho JD, Michailowsky V, Oliveira Mde F, Queiroz JÁ (2015) Clinical and epidemiological profile of elderly patients with Chagas disease followed between 2005-2013 by pharmaceutical care service in Ceará State, Northeastern Brazil. Revista do Instituto de Medicina Tropical de Sao Paulo 57:145-52

Freitas EC, Oliveira Mde F, Andrade MC, Vasconcelos AS, Silva Filho JD, Cândido Dda S, Pereira Ldos S, Correia JP, Cruz JN, Cavalcanti LP (2015) Prevalence of chagas disease in a rural area in the state of Ceara, Brazil. Revista do Instituto de Medicina Tropical de Sao Paulo 57:431-3

Andrade MC, Oliveira Mde F, Nagao-Dias AT, Coêlho IC, Cândido Dda S, Freitas EC, Coelho HL, Bezerra FS (2013) Clinical and serological evolution in chronic Chagas disease patients in a 4-year pharmacotherapy follow-up: a preliminary study. Revista da Sociedade Brasileira de Medidicina Tropical 46:776-8