Bernardo Gutiérrez

DPhil Student

Department of Zoology

University of Oxford

Peter Medawar Building

South Parks Road

Oxford, OX1 3SY, UK

My interests focus on the evolutionary genetics of zoonotic viruses and the application of different computational techniques to evaluate the predictability of spillover events from wild reservoir populations to humans. For this purpose, I plan to combine structural information of viral proteins and phylogenetic inference to analyse phenotypes associated with host jumps. I aim to evaluate this phenomenon across multiple viral families and determine whether the structural information can be integrated into viral phylogenetics to better understand viral zoonosis.

I am also a visiting researcher at the Universidad San Francisco de Quito in Ecuador, where I provide assistance in population genetic analyses for various plant and animal species.

Research Interests

Gutierrez B, Márquez S, Prado-Vivar B, Becerra-Wong M, Guadalupe JJ, da Silva Candido D, Fernandez-Cadena JC, Morey-Leon G, Armas-Gonzalez R, Andrade-Molina DM, Bruno A, de Mora D, Olmedo M, Portugal D, Gonzalez M, Orlando A, Drexler JF, Moreira-Soto A, Sander AL, Brünink S, Kühne A, Patiño L, Carrazco-Montalvo A, Mestanza O, Zurita J, Sevillano G, du Plessis L, McCrone JT, Coloma J, Trueba G, Barragán V, Rojas-Silva P, Grunauer M, Kraemer MUG, Faria NR, Escalera-Zamudio M, Pybus OG, Cárdenas P (2021) Genomic epidemiology of SARS-CoV-2 transmission lineages in Ecuador. Virus Evolution In press

Kraemer MUG, Hill V, Ruis C, Dellicour S, Bajaj S, McCrone JT, Baele G, Parag KV, Battle AL, Gutierrez B, Jackson B, Colquhoun R, O’Toole A, Klein B, Vespignani A, COVID-19 Genomics UK (CoG-UK) consortium, Volz E, Faria NR, Aanensen D, Loman NJ, du Plessis L, Cauchemez S, Rambaut A*, Scarpino SV, Pybus OG (2021) Spatio-temporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence. Science In press

du Plessis L, McCrone JT, Zarebski AE, Hill V, Ruis C, Gutierrez B, Raghwani J, Ashworth J, Colquhoun R, Connor TR, Faria NR , Jackson B, Loman NJ, O’Toole A, Nicholls SM, Parag  KV, Scher E, Vasylyeva TI, Volz EM, Watts A, Bogoch II, Khan K, COG-UK consortium, Aanensen DM, Kraemer MUG, Rambaut A, Pybus OG (2021) Establishment & lineage dynamics of the SARS-CoV-2 epidemic in the UK. Science 371:708–12

Kraemer MUG, Yang CH, Gutierrez B, Wu CH, Klein B, Pigott DM, Open COVID-19 Data Working Group, du Plessis L, Faria NR, Li R, Hanage WP, Brownstein JS, Layan M, Vespignani A, Tian H, Dye C, Pybus OG, Scarpino SV (2020) The effect of human mobility and control measures on the COVID-19 epidemic in China. Science 368:493–7

Gutierrez B, Wise EL, Pullan ST, Logue C, Bowden TA, Escalera-Zamudio M, Tueba G, Nunes MR, Faria NR, Pybus OG (2020) The evolutionary dynamics of Oropouche Virus (OROV) in South America. Journal of Virology 94:e01127–19

Wise EL, Márquez S, Mellors J, Paz V, Atkinson B, Gutierrez B, Zapata S, Coloma J, Pybus OG, Jackson SK, Trueba G, Fejer G, Logue CH, Pullan ST (2020) Oropouche virus cases identified in Ecuador using an optimised qRT-PCR informed by metagenomic sequencing. PLOS Neglected Tropical Diseases 14:e0007897

Gutierrez B, Escalera-Zamudio M, Pybus OG (2019) Parallel molecular evolution and adaptation in viruses. Current Opinion in Virology 34:90-96

Hill SC, de Vasconcelos JN, Gutierrez B, Thézé J, Jandondo D, Neto Z, Mirandela M, Sebastião CS, Cândido ALM, Clemente C, da Silva SP, de Oliveira T, Pybus OG, Faria NR, Afonso JM (2019) Early genomic detection of the cosmopolitan genotype of dengue virus 2 in Angola, 2018. Emerging Infectious Diseases In press

Cueva DF, Gutierrez B, Bruque G, Molina S, Torres ML (2018) Mitochondrial DNA reveals low genetic diversity in Ecuadorian Andean bears. Ursus 29:43-51

Cobo MM, Gutierrez B, Torres ML (2018) Regeneration of mortiño (Vaccinium floribundum Kunth) plants through axillary bud culture. In Vitro Cellular & Developmental Biology - Plant 54:112-16

Cobo MM, Gutierrez B, Torres AF, Torres ML (2016) Preliminary analysis of the genetic diversity and population structure of mortiño (Vaccinium floribundum Kunth). Biochemical Systematics & Ecology 64:14-21

Guadalupe JJ, Gutierrez B, Intriago-Baldeon DP, Arahana V, Tobar J, Torres AF, Torres ML (2015) Genetic diversity and distribution patterns of Ecuadorian capuli (Prunus serotina). Biochemical Systematics & Ecology 60:67-73

Salgado C, Arahana V, Tobar J, Gutierrez B, Torres ML (2013) Employing molecular markers to identify Monilinia fructicola in Ecuadorian peach orchards. Australasian Plant Disease Notes 8:149-152

Johnson MD, Burton NA, Gutierrez B, Painter K, Lund PA (2011) RcsB is required for inducible acid resistance in Escherichia coli and acts at gadE-dependent and independent promoters. Journal of Bacteriology 193:3653-56